r/vulvodynia 3d ago

Does anyone need info from the Goldstein et al. medical textbook "Female Sexual Pain Disorders"?

I now have the medical textbook by Goldstein et al. I had been wanting to get my hands on this for a while, since it gets a lot more detailed than their paperback When Sex Hurts.

For example, I have been curious about the role of ketamine in the amitriptyline-ketamine topical used for neuroproliferative vestibulodynia. (I thought perhaps it was just used to help with the initial burning pain upon application, but it sounds like it's not.) The book mentions that "in a non-controlled study for pelvic pain in both men and women, when [amitriptyline is] combined with ketamine, the results in terms for both tolerability and perceived pain reduction were promising". This doesn't give all the answers, but it was still helpful for me.

Does anyone have any deeper things they would like more information on? This is intended to be kind of nerdy and in-depth, and likely not as helpful for more surface level diagnosis questions.

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u/SnooWalruses2253 2d ago

Yes! Anything nerve related and provoked because I have dealt with it for 3 years 😭 I have read “when sex hurts”

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u/lola_rose00 2d ago

Did you book say more about what topicals help with neuroproliferate vulvodynia? Amitriptyline has previously burned me, so now I am trying gaba and ketamine, does it say anything about that? And does the medical Script say anything new about mast cells and treatment in correlation to neuroproliferate?

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u/justagirl_7410 Provoked vestibulodynia 1d ago

just got access through my library. thanks for the rec, looking forward to reading