r/afinil • u/LorKayatsu • Aug 13 '25

Does amino acids reduces the effects of modafinil and methylphenidate? NSFW

Hi everyone, I've been using methylphenidate and sometimes modafinil for narcolepsy on medical advice.

After much research on various Reddit threads, etc., I'm combining several substances, but never overdosing on methylphenidate above 20mg daily, in an attempt to prolong or increase the medication's effect.
Many combinations, I'm currently testing include, for example, L-tyrosine, ALCAR, NALT, and caffeine capsules. However, I recently read that excess acid in the blood can decrease the effects of methyl/moda. So, I'd like know anything about this or if you've tried them and noticed a difference in the medication.

By the way, i read that acidic drinks reduce the effects of methylphenidate/moda. Does anyone know if this is true?

Any opinion and combination is welcome ;)

5 Upvotes

100% Upvoted

3 comments sorted by

•

u/AutoModerator Aug 13 '25

This comment is automatically added to all posts for visibility

Reminder: Vendor and source discussion for modafinil/armodafinil/Flmodafinil is not allowed. If your post contains references to modafinil/armodafinil/Flmodafinil vendors or sources, please make sure they get removed.

I am a bot, and this action was performed automatically. Please contact the moderators of this subreddit if you have any questions or concerns.

1

u/sinisteraxillary Aug 15 '25

Excess acid? Define excess please.

This sounds suspiciously like woo

1

u/Spoztoast Aug 18 '25

The body works incredibly hard to maintain homeostasis, especially with blood acid levels between 7.35-7.45. I doubt this 0.1 variation will affect it much, if any.

Trying to mess with your blood acid levels will mess you up badly and fast.